Formulasi Sediaan Sabun Cair Ekstrak Daun Ramania (Bouea macrophylla Griffith) sebagai Antiseptik
DOI:
https://doi.org/10.29408/sinteza.v4i2.25475Keywords:
antiseptic, Extract, Bouea macrophylla Griffith, Liquid soapAbstract
Ramania leaves (Bouea macrophylla Griffith) are natural ingredients that have activity as an antiseptic. Ramania leaves contain flavonoids, alkaloids, steroids and tannins. This study aims to make antiseptic liquid soap from ramania leaf extract with a concentration of 5%, 10%, 15%. This study used experimental methods in the laboratory. three formulations were made (FI, FII, FIII with a concentration of 5%, 10%, 15%). Evaluation includes organoleptic, homogeneity, pH, specific gravity, foam height. Antiseptic test was carried out using the zigzag method. he antiseptic test was carried out using the replica method. The statistical test for evaluating preparations is One Way Anova, for antiseptic testing using Paired sample t-test. The results of several evaluations have met the requirements, except that the specific gravity does not meet the SNI criteria. The antiseptic test is indicated by the percentage of bacterial reduction. The percentage of bacterial reduction in FI, II, and III respectively was 40.5; 48.5; and 57.5%. It can be seen that increasing the extract concentration can reduce the number of bacterial colonies. The results of the One Way Anova statistical test (a = 0.05) showed that there was no difference in the results of the preparation evaluation, the results of the paired sample test (a = 0.05) showed a significant difference in the antiseptic test. Based on the results of research on the specific gravity test however all formulas do not meet the criteria. In the antiseptic test, all formulas were effective in inhibiting bacterial growth.
References
Adriani, D. (2017). The Influence of Hand Washing Audio Visual Media on Pre-School Children's Hand Washing Ability with Soap. Cendekia Medika Jombang.
Aiyuba, S. D., Rakhmatullah, N. A., & Restapaty, R. (2023). Test of Antioxidant Activity of Methanol Extract of Ramania Leaves (Bouea macropylla Griffith) Using the DPPH Method. Jurnal Surya Medika, 8(1).
Aqiila, G. R., Taufiqurrahman, I., & Wydiamala, E. (2017). Test of the Effectiveness of Ethanol Extract of Ramania Leaves (Bouea macrophylla Griffith) on the Mortality of Artemia salina Leach Larvae. Dentino: Jurnal Kedokteran Gigi, 2(2), 170–176.
Astari, D. I. (2021). The Effect of KOH Concentration and Antibacterial Activity Test of Liquid Hand Washing Soap Combination of Miana Leaf Extract and Kemuning Leaves on Staphyloccocus aureus and Escherichia coli Bacteria. Stikes Karya Putra Bangsa Tulungagung.
Conitaty, Y., & Hasyim, L. F. (2022). Antibacterial Effectiveness Test of Methanol Extract of Ramania Leaves (Bouea macrophylla Griffith) Against Staphylococcus aureus Bacteria. Pharmacoscript, 5(2), 212–224.
Dimpudus, S. A. (2017). Formulation of Antiseptic Liquid Soap with Ethanol Extract of Water Henna Flower (Impatiens balsamina L.) and Test of Its Effectiveness Against Staphylococcus aureus Bacteria In Vitro. Pharmacon, 6(3).
Indriaty, S., Firmansyah, D., & Imany, S.P. (2019). Liquid Bath Soap Formulation from Ethanol Extract of Temu Giring (Curcuma heyneana) with Cocamidopropyl Betaine Concentrations of 1.6% and 3.2%. Jurnal Farmagazine, 6(2).
Jayani, I. N., Kartini & Basirah, N. (2017). Formulation of Lime Extract Hand Soap (Citrus aurantifolia) and Its Effectiveness as an Antiseptic. Dapartemen Biologi Farmasi Surabaya, 1(4).
Khalishah, N., Oktiani, B. W., & Adhani, R. (2022). Antibacterial Effectiveness Test Of Ramania Leaves (Bouea macrophylla Griffith) Flavonoids Extract On Aggregatibacter actinomycetemcomitans Bacteria Causing Aggressive Periodontitis. Dentino: Jurnal Kedokteran Gigi, 6(1), 25–30.
Kumalasari, E., Susanto, Y., Rahmi, M. Y., & Febrianty, D. R. (2019). The Effect of Giving Ethanol Extract of Ramania Leaves (Bouea macrophylla Griffith) on Alloxan-Induced Reduction of Blood Sugar Levels of White Mice (Mus muscullus). JCPS (Journal of Current Pharmaceutical Sciences), 2(2), 173–179.
Listiadesti, A. U., Noer, S. M., & Maifita, Y. (2020). The Effectiveness of Video Media on Hand Washing Behavior with Soap in School Children: a Literature Review. Menara Medika, 3(1).
Mahdi, N., Putra, F., Manurung, N. (2022). Formulation and Activity Test of Antiseptic Liquid Soap from Kapul Fruit Skin Extract (Baccaurea macrocarpa). Jurnal Ilmiah Ibnu Sina, 7(1).
Manik, F. D., Hertiana, T., & Anshory, H. (2014). Correlation Analysis Between Flavonoid Levels and Antibacterial Activity of Ethanol Extract and Fractions of Kersen Leaves (Muntingia calabura L) Against Staphylacoccus aureus. Khazanah, 6(2).
Muna, T., Zakaria, N., Fonna, L. (2021). Formulation and Evaluation of Patchouli Leaf (Pogostemon cablin Benth) Essential Oil Liquid Soap. Jurnal Sains & Kesehatan Darussalam, 1(1).
Murti., Putra., Saputri, N., Wijayanti, N. P., & Yustiantara. (2017). Optimizing Olive Oil Concentration on the Physical Stability of Liquid Soap Preparations. Jurnal Farmasi Udayana, 6(2).
Nurhasanah., & Gultom, S. E. (2020). Antibacterial Activity Test of Methanol Extract of Kirinyuh Leaves (Chromolaena odorata) Against MDR (Multi Drug Resistant) Bacteria Using the TLC Bioautography Method. The Journal of Biosciences, 6(2).
Qomariyah, L., Panjaitan, F. U. A., & Adhani, R. (2021). Antibacterial Effectivity Of Flavonoid Fraction Of Ramania Leaf Extract (Bouea macrophylla Griffith) Against Porphyromonas gingivalis. Dentino: Jurnal Kedokteran Gigi, 6(1), 72–78.
Rahayu, Y. P., Lubis, M. S., & Mutti-in, K. (2021). Formulation of antiseptic liquid soap with papaya seed extract (Carica papaya L.) and test of its antibacterial effectiveness against Staphylococcus aureus. Prosiding Seminar Nasional Hasil Penelitian, 4(1), 373–388.
Sahambangung, M., Datu, O., Tiwow, G., & Potolangi, N. (2019). Formulation of antiseptic soap preparation from Carica papaya papaya leaf extract. Biofarmasetikal Tropis, 2(1), 43–51.
Salsabila, F. (2022). Optimization of Making Cananga (Cananga odorata) Preparations Based on Different Heating Temperatures. Politeknik Harapan Bersama Tegal, 50-52.
Setiawati, I., & Ariani, A. (2020). Study of pH and Contents in SNI Solid Bath Soap in Jabedebog. Prosiding PPIS Tanggerang Selatan.
Widyasanti, A., Rahayu, Y.A., & Zain, S. (2017). Pembuatan Sabun Cair Berbasis Virgin Coconut Oil (VCO) dengan Penambahan Minyak Melati (Jasminum sambac) Sebagai Essential oil. Jurnal Teknotal universitas padjadjaran, 11(2).
Yamlean, V. P., & Bodhi, W. (2017). Formulasi dan Uji Antibakteri Sediaan Sabun Cair Ekstrak Daun Kemangi (Ocymum basilicum L) Terhadap Bakteri Staphylacoccus aureus. Jurnal Ilmiah Farmasi, 6(1).
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Sinteza
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish in Sinteza, agree to retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, web sites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
2.png)
